Graphene based gene transfection

Author: vsno

August undefined, 2024

WebMar 1, 2011 · Graphene as a star in materials research has been attracting tremendous attentions in the past few years in various fields including biomedicine. In this work, for … WebIn general, it can be concluded that polymer-functionalized graphene-based carriers have been widely applied in gene delivery to treat various diseases including cancer, 251 osteoporosis, 252 and myocardial infarction. 253 A variety of macromolecules including cationic polymers, dendrimers, chitosan, and peptides have been used to modify ...

Targeted delivery of reduced graphene oxide nanosheets using ...

WebApr 12, 2024 · Polymeric gene carriers target the nucleus and express their therapeusis through transcription and translation . Gene carriers are either viral vectors (retro-viruses and adenoviruses) or non-viral vectors. Viral vectors submit their genetic materials to the host cells and are known to attain greater transfection . 18.3.1.2 Polymeric Micelles WebThe use of NA is gaining increasing interest and more than 2000 clinical trials of NA-based therapies are underway. 2 The current advancements in medicine, biology and biotechnology have extended the scope of gene therapy from the “simple” transfection of plasmid DNA (pDNA) to the delivery of a variety of NA, including short interfering RNA ... diabetes and dementia symptoms

Graphene materials as 2D non-viral gene transfer vector platforms …

WebDec 4, 2024 · The objective of this study is to design a graphene-based miRNA transfection drug delivery system for antiresorptive therapy. An efficient nonviral gene … WebOct 13, 2014 · Graphene based biosensors make use of two strategies-1) probe molecule on graphene interacts with the analyte (FRET based ... Zhang S, Liu Z (2011) Graphene based gene transfection. Nanoscale 3: 1252-1257. Zhou L, Wang W, Tang J, Zhou JH, Jiang HJ, et al. (2011) Graphene oxide noncovalent photosensitizer and its anticancer … WebJan 23, 2024 · Recently graphene has been used in biomedical applications including DNA sequencing 10, biosensor development 11, and graphene-enhanced cell differentiation … cincycan.org

Graphene based gene transfection - Nanoscale (RSC Publishing)

Graphene and its derivatives as biomedical materials: future …

WebFeng, L., Zhang, S., & Liu, Z. (2011). Graphene based gene transfection. Nanoscale, 3(3), 1252. doi:10.1039/c0nr00680g WebFeb 28, 2024 · Feng L Zhang S Liu Z Graphene based gene transfection Nanoscale 2011 33 1252 1257 21270989 , [Web of Science ®], [Google Scholar] Yang X Wang Y Huang X Multi-functionalized graphene oxide based anticancer drug-carrier with dual-targeting function and pH-sensitivity J Mater Chem 2011 2110 3448 3454 , [Web of Science ®], … diabetes and dementia linkWebJan 15, 2024 · Graphene and graphene-based nanomaterials such as graphene oxide (GO), reduced graphene oxide (rGO) and graphene quantum dots (GQDs) ... Feng, S. Zhang and Z. Liu, Graphene based gene transfection, Nanoscale 3 (2011) 1252–1257. cincy burner

"WebGene therapy has been found to hold tremendous potential for the treatment of cancers beyond conventional methods. 30–32 Nonviral vector provides safer methods without the potential side effects of viral transfection, such as immunogenicity and carcinogenesis. 33 GO has been considered an ideal vector for gene delivery. 34,35 In this study ... " - Graphene based gene transfection

Graphene based gene transfection

WebJun 1, 2014 · Abstract. Graphene and carbon nanotube nanocomposite (GCN) was synthesised and applied in gene transfection of pIRES plasmid conjugated with green fluorescent protein (GFP) in NIH-3T3 and NG97 cell lines. The tips of the multi-walled carbon nanotubes (MWCNTs) were exfoliated by oxygen plasma etching, which is also … WebOur results suggest graphene to be a novel gene delivery nano-vector with low cytotoxicity and high transfection efficiency, promising for future applications in non-viral based …

Did you know?

WebAug 18, 2024 · Deoxyribonucleic acid (DNA) vaccines are a promising cancer immunotherapy approach. However, effective delivery of DNA to antigen-presenting cells (e.g., dendritic cells (DCs)) for the induction of an adaptive immune response is limited. Conventional DNA delivery via intramuscular, intradermal, and subcutaneous injection by … WebTo evaluate the transfection efficiency of NGQDs, we delivered mRNA into HeLa cells with NGQDs. As shown in Figure 4 a, the NGQDs formed complexes with mRNA at a 20:1 …

WebJan 27, 2011 · Our results suggest graphene to be a novel gene delivery nano-vector with low cytotoxicity and high transfection efficiency, promising for future applications in non … WebDec 4, 2024 · The objective of this study is to design a graphene-based miRNA transfection drug delivery system for antiresorptive therapy. An efficient nonviral gene delivery system is developed using polyethylenimine (PEI) functionalized graphene oxide (GO) complex loaded with miR-7b overexpression plasmid.

WebJan 21, 2016 · During PhD work, I extensively involved on the development of chitosan based novel non-viral vectors for gene therapy application. I developed polyamidoamine (PAMAM) dendrimer conjugated chitosan copolymer through various chemical methods and showed very high transfection efficiency. All my research works published in reputed … WebApr 20, 2024 · Graphene-based nanomaterials have been used as scaffolds for cell culture and tissue engineering and have exhibited minimal harmful effect on the mammalian cells, very good adhesion properties, excellent gene transfection efficacy, high capability of the promotion of differentiation of stem cells into bone cells in a controlled manner for bone ...

WebGraphene as a star in materials research has been attracting tremendous attentions in the past few years in various fields including biomedicine. In this work, for the first time we … cincy burgersWebMany researchers have tried to transfect genes using carbon-based materials such as graphene oxides (GOs) and graphene quantum dots (GQDs) [29,30,31,32]. ... Prior to in vitro gene transfection with NGQDs, we verified the cytotoxicity of the NGQDs via a CCK-8 assay kit. For the CCK-8 assay, various concentrations of NGQDs from 1 μg/mL to 1000 ... diabetes and depression pakistanWebVisualizing The Localization Of Transfection Complexes During Graphene Nanoparticle-Based Transfection Journal of Materials Chemistry B … cincy brewing company cincinnati ohWebNov 22, 2016 · The extraordinary physicochemical, optical and photothermal properties of graphene-based materials (GBMs) could offer two-dimensional components for the design of nucleic acid carrier systems. cincy cagesWebGraphene as a star in materials research has been attracting tremendous attentions in the past few years in various fields including biomedicine. In this work, for the first time we successfully use graphene as a non-toxic nano-vehicle for efficient gene transfection. diabetes and depression ssdiWebDec 4, 2024 · In treating osteoporotic ovariectomized mice, GO‐PEI‐miR‐7b significantly enhances bone mineral density, bone volume as well as bone vascularization through increasing CD31hiEmcnhi cell number. The objective of this study is to design a graphene‐based miRNA transfection drug delivery system for antiresorptive therapy. … cincycakeand cancy.comWebJul 30, 2024 · Methods: Graphene oxide/APTES was modified by spermine (GOAS) and characterized by FT-IR, DLS, SEM and AFM techniques. Then pEGFP-p53 was loaded on GOAS, transfected into cells and evaluated by fluorescent microscopy and gene expression techniques. Results: FT-IR data approved the GOAS sheet formation. Ninety percent of … cincy-caa.org