Christopher vakoc
WebMeet Dr. Christopher Vakoc Inventing new cancer medicines Cancer cells achieve their pathogenicity by changing which genes are on and off. To maintain these changes in gene expression, cancer cells rely on proteins that interact with DNA or modify chromatin. WebPlasmid pHAGE_puro from Dr. Christopher Vakoc's lab is published in Cancer Cell. 2024 Dec 10;34(6):970-981.e8. doi: 10.1016/j.ccell.2024.10.015. Epub 2024 Nov 29. This plasmid is available through Addgene. Image: Illustrated plasmid map in PNG format. GenBank File: Plasmid sequence and annotations. Use text editor or plasmid mapping software to ...
Christopher vakoc
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WebFeb 24, 2024 · Vakoc and his colleagues became excited about ETV6 when their experiments revealed that Ewing sarcoma cells seem uniquely dependent on this protein. “This protein is present in all cells. But... WebMar 3, 2024 · Christopher R. Vakoc 1Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, U.S.A Find articles by Christopher R. Vakoc Author informationCopyright and License informationDisclaimer 1Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, U.S.A 2Genetics Program, Stony Brook University, Stony Brook, NY 11794, U.S.A
WebOct 25, 2024 · CSHL Professor Christopher Vakoc and his lab discovered that acute myeloid leukemia cells depend on a single transporter to get the essential sugar inositol … WebVakoc graduated with a degree in Biochemistry from Pennsylvania State University in 2001. He then attained his M.D. and his Ph.D. from the University of Pennsylvania. His PhD …
WebApr 12, 2024 · EN1 predominantly repressed its target genes through direct binding to gene enhancers and promoters, implicating a role in the acquisition of mesenchymal cell …
WebChristopher Vakoc Publication Huang et al. Genes Dev. 2024 Jul 1;32 (13-14):915-928. doi: 10.1101/gad.314815.118. ( How to cite ) Ordering Available to Academic and Nonprofits Only † A Cas9 plasmid is NOT included with this item and will have to …
WebJan 19, 2024 · New treatments are badly needed, says CSHL Professor Christopher Vakoc, who led the research on ETV6. Vakoc and his colleagues became excited about ETV6 when their experiments revealed that... tfs 260 headsWebSep 1, 2015 · Anand S Bhagwat 1 , Christopher R Vakoc 1 Affiliation 1 Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA. PMID: 26645049 PMCID: PMC4669894 DOI: 10.1016/j.trecan.2015.07.001 Abstract Transcription factors (TFs) are commonly deregulated in the pathogenesis of human cancer and are a major … tfs 225 ls headsWebThe Vakoc Laboratory Cancer Drug Target Discovery and Mechanisms Our lab seeks to discover drug targets by applying genetic screens to human cancer cells. This genetic … sylvania sbt225 headphonesWebMar 15, 2024 · Here, we used a domain-focused CRISPR screen to reveal an essential role for LKB1 and its Salt-Inducible Kinase effectors (SIK3, in a partially redundant manner with SIK2) to maintain MEF2C function in acute myeloid leukemia (AML). A key phosphorylation substrate of SIK3 in this context is HDAC4, a repressive cofactor of MEF2C. sylvania schools oneview parent portalWebThe Christopher Vakoc Lab has deposited materials at Addgene for distribution to the research community. Addgene is a nonprofit plasmid repository dedicated to improving … tfs 2604 training grantWebChristopher R Vakoc A highly aggressive subset of pancreatic ductal adenocarcinomas undergo trans-differentiation into the squamous lineage during disease progression. tfs 240 high port headsWebChristopher R. Vakoc's 203 research works with 19,068 citations and 12,570 reads, including: ETV6 dependency in Ewing sarcoma by antagonism of EWS-FLI1-mediated enhancer activation tfs 245 heads